The New England Journal of Medicine • April 15 2021
In The Doors of Perception, Aldous Huxley described his trial of mescaline as “the most extraordinary and significant experience available to human beings this side of the Beatific Vision.” His exegesis was preceded by the synthesis of the hallucinogen lysergic acid diethylamide (LSD) by Sandoz chemist Albert Hoffman in 1938 and was followed by Hoffman’s extraction of psilocybin from Psilocybe mexicana in 1959.
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